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Therapy of B-cell lymphomas with monoclonal antibodies and radioimmunoconjugates: the Seattle experience

โœ Scribed by T. A. Johnson; O. W. Press

Publisher
Springer
Year
2000
Tongue
English
Weight
148 KB
Volume
79
Category
Article
ISSN
0939-5555

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โœ Stefano Sacchi; Massimo Federico; Giuseppe Dastoli; Claudia Fiorani; Giovanni Vi ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 232 KB

Rituximab is a chimeric anti CD-20 monoclonal antibody containing human IgG1 kappa constant regions, with murine variable regions. The anti-lymphoma effects of Rituximab are probably due to complement and antibody-dependent cell-mediated cytotoxicity, and induction of apoptosis. Phase II trials have