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Therapy for metastatic colorectal carcinoma with a combination of methyl-CCNU, 5-fluorouracil vincristine and streptozotocin (MOF-strep)

โœ Scribed by N. Kemeny; A. Yagoda; D. Braun Jr; R. Golbey


Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
535 KB
Volume
45
Category
Article
ISSN
0008-543X

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๐Ÿ“œ SIMILAR VOLUMES


Metastatic colorectal carcinoma: A prosp
โœ Nancy Kemeny; Alan Yagoda; David Braun Jr. ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 442 KB ๐Ÿ‘ 2 views

A Prospective Randomized Trial of Methyl-CCNU, 5-Fluorouracil (5-FU) and Vincristine (MOF) Versus MOF Plus Streptozotocin (MOF-Strep) A prospective randomized trial evaluated semustine (Methyl CCNU) 5-Fluorouracil (5-FU) and vincristine (MOF) versus MOF plus streptozotocin (MOF-Strep) in 75 patients

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The combination of 5-fluorouracil (5-FU), methyl-1,3-cis(2-chlorethyl)-1-nitrosourea (methylCCNU), and vincristine (VCR) has been reported to produce a 43.5% response rate in metastatic colorectal cancer, although subsequent studies did not produce such good response rates. The clinical trial report