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Therapeutic Monoclonal Antibodies || Production of Antibody Fab′ Fragments inE. coli

✍ Scribed by An, Zhiqiang

Book ID
120219275
Publisher
John Wiley & Sons, Inc.
Year
2009
Weight
292 KB
Category
Article
ISBN
0470117915

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A new method for the production of monovalent Fab fragments of antibodies has been developed. Traditionally Fab fragments are produced by proteolytic digestion of antibodies in solution followed by isolation of Fab fragments. In the case of monoclonal antibodies against inactivated subunits of glyce