Therapeutic Monoclonal Antibodies || Characterization of Heterogeneity in Monoclonal Antibody Products
β Scribed by An, Zhiqiang
- Book ID
- 120387918
- Publisher
- John Wiley & Sons, Inc.
- Year
- 2009
- Weight
- 553 KB
- Category
- Article
- ISBN
- 0470117915
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π SIMILAR VOLUMES
Heterogeneity of monoclonal antibodies is common due to the various modifications introduced over the lifespan of the molecules from the point of synthesis to the point of complete clearance from the subjects. The vast number of modifications presents great challenge to the thorough characterization
The specificity of antibodies has been harnessed to target cancer cells and the first therapeutic antibodies for use in oncology are now finding application in the clinic. Studies are currently under way to develop new and improved antibodies. Recent developments have been made in the identification