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Therapeutic implications of iodine-125 cytotoxicity

โœ Scribed by William D. Bloomer; William H. McLaughlin; S. James Adelstein

Book ID
103720023
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
791 KB
Volume
8
Category
Article
ISSN
0360-3016

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โœ W. D. Bloomer; W. H. McLaughlin; R. A. Milius; R. R. Weichselbaum; S. J. Adelste ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 329 KB

Auger effects from 1251 decay are singularly damaging if localized in DNA as the thymidine analogue 1251-iododeoxyuridine ( '251UdR). Recent experience with steroid sex hormones extends these observations by demonstrating cytotoxicity in sites other than the DNA backbone. We have compared the cytoto