Therapeutic efficacy of L-asparaginase in the treatment of refractory midfacial peripheral T-cell non-hodgkin’s lymphoma
✍ Scribed by Wei-ben Yong; Yun-tao Zhang; Wen Zheng; Yan Wei; Jun Zhu
- Publisher
- Chinese Anti-Cancer Association
- Year
- 2000
- Tongue
- English
- Weight
- 233 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1000-9604
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A polyethylene glycol conjugate of L-asparaginase (PEGLA) was administered to 21 patients with refractory non-Hodgkin's lymphoma. The dose given was 2,000 mu/m2 intramuscularly every 2 weeks. Eligibility required at least one prior trial of chemotherapy and ambulatory performance status. At entry, a
Therapy with recombinant interleukin-2 (rIL-2) induces clinical response in a significant number of patients with refractory malignant disease. Very few patients with non-Hodgkin's lymphoma (NHL) have been treated with rIL-2. The present study sought to determine if peripheral blood mononuclear cell