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L-Asparaginase in the treatment of refractory and relapsed extranodal NK/T-cell lymphoma, nasal type

✍ Scribed by Weiben Yong; Wen Zheng; Jun Zhu; Yuntao Zhang; Xiaopei Wang; Yan Xie; Ningjing Lin; Bo Xu; Aiping Lu; Jiyou Li


Publisher
Springer
Year
2008
Tongue
English
Weight
125 KB
Volume
88
Category
Article
ISSN
0939-5555

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Purpose: Midline NK / T-cell lymphoma nasal-type is an aggressive neoplasm with poor prognosis in most instances. To improve the treatment outcome, we have tried using L-asparaginase based regimen as salvage regimen plus radiation in CHOP failures, and report here the therapeutic results and prognos

Immunohistochemical expression and clini
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## Abstract Overexpression of P‐glycoprotein (P‐gp) has been identified by a variety of methods in NK cells and NK malignancies. The aim of this study was to determine the clinical significance of P‐gp in previously untreated extranodal NK/T‐cell lymphoma, nasal type. Tumor specimens from 30 patien