## Abstract ## Background Rats with experimental Parkinson's disease (PD) are treated with intravenous glial‐derived neurotrophic factor (GDNF) plasmid DNA, non‐viral gene therapy using Trojan horse liposomes (THLs) targeted with a monoclonal antibody (MAb) to the rat transferrin receptor (TfR). E
✦ LIBER ✦
Therapeutic effects of astrocytes expressing both tyrosine hydroxylase and brain-derived neurotrophic factor on a rat model of Parkinson’s disease
✍ Scribed by Z.H Wang; Y Ji; W Shan; B Zeng; N Raksadawan; G.M Pastores; T Wisniewski; E.H Kolodny
- Book ID
- 117490570
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 628 KB
- Volume
- 113
- Category
- Article
- ISSN
- 0306-4522
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## Abstract The clinical symptoms of Parkinson's disease (PD) appear late and only when the degenerative process at the level of the nigrostriatal dopamine (DA) pathway is quite advanced. An increase in brain‐derived neurotrophic factor (BDNF) expression may be one of the molecular signals associat
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