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Efficacy of Tyrosine Hydroxylase gene modified neural stem cells derived from bone marrow on Parkinson's disease – a rat model study

✍ Scribed by Zhihao Zou; Xiaodan Jiang; Wangming Zhang; Yuan Zhou; Yiquan Ke; Shizhong Zhang; Ruxiang Xu


Book ID
113505050
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
1003 KB
Volume
1346
Category
Article
ISSN
0006-8993

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## Abstract Parkinson's disease (PD) is a neurodegenerative disease characterized by progressive degeneration of nigrostriatal dopaminergic (DA) neurons. The therapeutic potential of glial cell line‐derived neurotrophic factor (GDNF), the most potent neurotrophic factor for DA neurons, has been dem