## Abstract ## Objective Adjuvant arthritis can be induced in Lewis rats by immunization with __Mycobacterium tuberculosis__ (Mt). The mycobacterial 65‐kd heat‐shock protein (Hsp65) is targeted by arthritogenic T cells. However, Hsp65 and the mycobacterial 71‐kd heat‐shock protein are also recogni
✦ LIBER ✦
Therapeutic effect of recombinant vaccinia virus expressing the 60-kd heat-shock protein on adjuvant arthritis
✍ Scribed by José Antonio López-Guerrero; Maria Antonia Ortiz; Eduardo Páez; Carmelo Bernabéu; Juan Pedro López-Bote
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 565 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0004-3591
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To assess the claim that the human 60-kd heat-shock protein (HSP) is highly expressed in the joints of patients with rheumatoid arthritis (RA), but is not readily detected in normal tissues. Methods. Monoclonal antibodies were raised against the human 60-kd mitochondria1 heat-shock protein (P1 prot