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Therapeutic applications of conotoxins that target the neuronal nicotinic acetylcholine receptor

✍ Scribed by Bruce G. Livett; David W. Sandall; David Keays; John Down; Ken R. Gayler; Narmatha Satkunanathan; Zeinab Khalil

Book ID
116921646
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
890 KB
Volume
48
Category
Article
ISSN
0041-0101

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## Abstract α‐Conotoxins, from cone snails, and α‐neurotoxins, from snakes, are competitive inhibitors of nicotinic acetylcholine receptors (nAChRs) that have overlapping binding sites in the ACh binding pocket. These disulphide‐rich peptides are used extensively as tools to localize and pharmacolo