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Theoretical Study of the Unusual Protonation Properties of the Active Site Cysteines in Thioredoxin

✍ Scribed by Carvalho, Alexandra T. P.; Fernandes, Pedro A.; Ramos, Maria J.

Book ID: 126094869
Publisher: American Chemical Society
Year: 2006
Tongue: English
Weight: 388 KB
Volume: 110
Category: Article
ISSN: 0022-3654
DOI: 10.1021/jp053275f

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## Abstract Thioredoxin superfamily members share a considerable degree of structural similarity, with a conserved CX~i~X~j~C motif at the active site, where C stand for two cysteines that alternate between a reduced thiol and oxidized disulfide states, and X~i~and X~j~ are two amino acids differen

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