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Theoretical Studies of the Effect of Thio Substitution on Orotidine Monophosphate Decarboxylase Substrates

โœ Scribed by Phillips, Linda M.; Lee, Jeehiun K.


Book ID
125953793
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
496 KB
Volume
70
Category
Article
ISSN
0022-3263

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A potential alternate substrate for orotidine-5ะˆ-monophosphate decarboxylase, 2-thio-orotidine-5ะˆ-monophosphate, was synthesized enzymatically and purified by a modification of a previous account (K. Shostak, and M. E. Jones 1992, Biochemistry 31, 12155-12161). Characterization of the product was co