Theophylline bioavailability in the dog
β Scribed by Francis L. S. Tse; Daniel W. Szeto
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 375 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Selegiline is beneficial to Parkinsonian patients as an adjunct to levodopa therapy. Currently no pharmacokinetic data are available for selegiline in the literature, mainly due to lack of analytical methods that can measure concentrations below 10 ng mL-' in plasma. A sensitive fluorimetric assay b
The role of the kidneys in the elimination of theophylline was directly assessed using nephrectomized dogs. Data was analyzed by two different pharmacokinetic approaches. Analysis indicated that a given dosage regimen produced significantly different serum concentrations before and after nephrectomy