We propose a simple mathematical model of liver S-adenosylmethionine (AdoMet) metabolism. Analysis of the model has shown that AdoMet metabolism can operate under two di!erent modes. The "rst, with low metabolic rate and low AdoMet concentration, serves predominantly to supply the cell with AdoMet,
Themeta-hydroxylation step in the phenylpropanoid pathway: a new level of complexity in the pathway and its regulation
✍ Scribed by Guillaume A. Schoch; Marc Morant; Nawroz Abdulrazzak; Carole Asnaghi; Simon Goepfert; Maike Petersen; Pascaline Ullmann; Danièle Werck-Reichhart
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 755 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1610-3653
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Mammalian target of rapamycin (mTOR) is a protein serine‐threonine kinase that functions as a central element in signaling pathway involved in control of cell growth and proliferation. mTOR exists in at least two distinct multi‐protein complexes, mTORC1 and mTORC2. mTOR kinase controls
## Abstract Zearalenone (ZEN) is a common mycotoxin, for which only reductive metabolites have been identified so far. We now report that ZEN is extensively monohydroxylated by microsomes from human liver __in vitro__. Two of the major oxidative metabolites arise through aromatic hydroxylation and
## Abstract Well‐coupled mitochondria were isolated from a HuH13 line of human hepatoma cells and human liver tissue. The liver mitochondria showed a feeble glutamine oxidation activity in contrast to the hepatoma mitochondria, whereas they utilized glutamate well for the oxidative phosphorylation.