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The β-lactam antibiotics, penicillin-G and cefoselis have different mechanisms and sites of action at GABAA receptors

✍ Scribed by Masahiro Sugimoto; Sakae Fukami; Hiroshi Kayakiri; Shunji Yamazaki; Nobuya Matsuoka; Ichiro Uchida; Takashi Mashimo


Book ID
110007086
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
157 KB
Volume
135
Category
Article
ISSN
0007-1188

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## Abstract Our aim was to use a conformational analysis technique developed for peptides to identify structural relationships between bacterial cell wall peptides and β‐lactam antibiotics that might help to explain their different actions as substrates and inhibitors of penicillin binding proteins