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The α2ß1 integrin binds to the CB4 peptide of the α2(I) collagen chain

✍ Scribed by William D. Staatz; John J. Walsh; Samuel A. Santoro

Book ID
111742428
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
339 KB
Volume
42
Category
Article
ISSN
1521-6543

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Adhesion to collagens by most cell types is mediated by the integrins a1b1 and a2b1. Both integrin a subunits belong to a group which is characterized by the presence of an I domain in the N-terminal half of the molecule, and this domain has been implicated in the ligand recognition. Since purified