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The α2-adrenoceptor antagonists idazoxan and yohimbine can unmask the postsynaptic dopamine agonist effects of B-HT 920

✍ Scribed by Leonard T. Meltzer; James N. Wiley; Thomas G. Heffner


Book ID
115882182
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
218 KB
Volume
170
Category
Article
ISSN
0014-2999

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Herein, we evaluate the interaction of the ␣ 2 -AR antagonist, yohimbine, as compared to fluparoxan, at multiple monoaminergic receptors and examine their roles in the modulation of adrenergic, dopaminergic and serotonergic transmission in freelymoving rats. Yohimbine displays marked affinity at hum