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The X-ray structure of a growth hormone–prolactin receptor complex

✍ Scribed by Somers, William; Ultsch, Mark; De Vos, Abraham M.; Kossiakoff, Anthony A.

Book ID
109790503
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
686 KB
Volume
372
Category
Article
ISSN
0028-0836

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## Abstract The MM‐PBSA (Molecular Mechanics–Poisson–Boltzmann surface area) method was applied to the human Growth Hormone (hGH) complexed with its receptor to assess both the validity and the limitations of the computational alanine scanning approach. A 400‐ps dynamical trajectory of the fully so