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Rational Design of Competitive Prolactin/Growth Hormone Receptor Antagonists

✍ Scribed by Estelle Tallet; Vincent Rouet; Jean-Baptiste Jomain; Paul A. Kelly; Sophie Bernichtein; Vincent Goffin


Book ID
106420163
Publisher
Springer US
Year
2008
Tongue
English
Weight
406 KB
Volume
13
Category
Article
ISSN
1083-3021

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Growth hormone (GH) and prolactin (PRL) exert their regulatory functions in the mammary gland by acting on specific receptors. Using isotopic in situ hybridization and immunohistochemistry, we have localized the expression of hGH receptor (hGHR) and hPRL receptor (hPRLR) in a panel of human breast d