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The Wnt receptor FZD1 mediates chemoresistance in neuroblastoma through activation of the Wnt/β-catenin pathway

✍ Scribed by Flahaut, M; Meier, R; Coulon, A; Nardou, K A; Niggli, F K; Martinet, D; Beckmann, J S; Joseph, J-M; Mühlethaler-Mottet, A; Gross, N

Book ID
109972293
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
293 KB
Volume
28
Category
Article
ISSN
0950-9232

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## Abstract The WNT/β‐catenin pathway is involved in numerous human cancers. Mutations of the __CTNNB1__ (β‐catenin) gene have also been detected in a subset of pediatric Wilms tumors, but the target genes of the deregulated WNT/β‐catenin pathway in these tumors have yet to be identified. To compar