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Tumor formation due to abnormalities in the β-catenin-independent pathway of Wnt signaling

✍ Scribed by Akira Kikuchi; Hideki Yamamoto

Book ID
108584070
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
488 KB
Volume
99
Category
Article
ISSN
1347-9032

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## Abstract The WNT/β‐catenin pathway is involved in numerous human cancers. Mutations of the __CTNNB1__ (β‐catenin) gene have also been detected in a subset of pediatric Wilms tumors, but the target genes of the deregulated WNT/β‐catenin pathway in these tumors have yet to be identified. To compar