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The Westphalen Rearrangement of 5α,6α-Epoxy-3β-methanesulfonyloxyandrostan-17-one.

✍ Scribed by Steve G. Knights; James R. Hanson


Publisher
John Wiley and Sons
Year
2005
Weight
21 KB
Volume
36
Category
Article
ISSN
0931-7597

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A Solution-Phase Combinatorial Parallel Synthesis of 3β-Amido-3α-hydroxy-5α-androstane-17-ones. -A two-level library of title compounds (IV) is prepared via reaction of oxirane (I) with 4 primary amines followed by treatment of each set with 4 aliphatic acyl chlorides. The purities of the products