## Abstract In myeloid malignancies, chromosome rearrangements involving band 3q21 are associated with a particularly poor prognosis of the disease. Their sensitive and unequivocal detection is therefore of great clinical importance. In this report, we describe the establishment of an interphase fl
The value of interphase fluorescence in situ hybridization for the detection of translocation t(12;21) in childhood acute lymphoblastic leukemia
β Scribed by G. Ameye; C. Jacquy; A. Zenebergh; M. Stul; J.-L. Vaerman; C. Bilhou-Nabera; J.-M. Libouton; V. Deneys; P. Martiat; A. Hagemeijer; G. Cornu; C. Verellen-Dumoulin; L. Michaux
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 236 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0939-5555
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## BACKGROUND. The cytomorphologic diagnosis of mantle cell lymphoma (MCL) can be difficult and requires ancillary studies for accurate subclassification. More than 95% of MCLs are known to carry the t(11;14) chromosomal translocation. However, traditional cytogenetic studies on cytologic material
## Abstract In situ hybridization was performed in a case of acute monoblastic leukemia (FAB type M5b) with a rearrangement of the long arm of chromosome 11. Cytogenetic analysis after Rβ and Gβbanding showed an apparent deletion of 11q with a breakpoint at 11q23, and a translocation t(6;11) was su
## BACKGROUND. Diagnosing lymphoproliferative disorders on fine-needle aspiration (FNA) can be challenging due to variable cellularity and lack of architecture. Ancillary studies often are required for diagnosis. Follicular lymphoma (FL) is characterized by a monoclonal B-cell proliferation with
## BACKGROUND. Mantle cell lymphoma can be difficult to differentiate cytologically from other small cell non-Hodgkin lymphomas. Nevertheless, the distinction is important, because mantle cell lymphoma is more aggressive than other small cell non-Hodgkin lymphomas. The purpose of this study was to
## Abstract Interphase fluorescence in situ hybridization (IβFISH) studies have a remarkable prognostic value in patients with chronic lymphocytic leukemia (CLL). IβFISH studies can be performed either on tetradecanoylphorbol acetate stimulated peripheral blood cells (IβFISHβTPA) or unstimulated pe