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The value of fluorescence markers in the distinction between maternal and fetal chromosomes

โœ Scribed by M. Hauge; Hanne Poulsen; Annie Halberg; Margareta Mikkelsen

Publisher
Springer
Year
1975
Tongue
English
Weight
259 KB
Volume
26
Category
Article
ISSN
0340-6717

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โœฆ Synopsis

Selected fluorescence markers of chromosomes were studied in 50 paired samples of cells obtained by culture of amniocentesis material and by culture of leukocytes from pregnant women. Comparative analyses showed that this method is of great value in disclosing admixture of maternal cells to material obtained by amniocentesis, as a minimum of 2 fluorescence marker differences between mother and fetus was found in the present material. The distribution of markers in mother/fetus pairs is in agreement with the assumption of genetic determination. Variation was observed between populations with respect to the frequency of the markers studied.

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