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Study of the origin of nondisjunction in

Study of the origin of nondisjunction in a family with two cases of Down syndrome using cytogenetic and molecular polymorphisms

✍ Stinissen, Piet ;Van Roy, Bernadette ;Van Camp, Guy ;Backhovens, Hubert ;Partoen 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 400 KB 👁 2 views

We analyzed the possibility of inherited predisposition to nondisjunction in a family with two cases of Down syndrome using restriction fragment length polymorphisms and cytogenetic heteromorphisms. In both patients the extra chromosome 21 was the result of a nondisjunction event at first meiotic di