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The use of tritiated prostaglandins in metabolism studies II: Kinetic isotopic effect: An useful tool to investigate catabolizing sequence of prostaglandins

✍ Scribed by C. Moussard; D. Alber; C. Perruche; J.C. Henry


Book ID
119050304
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
294 KB
Volume
31
Category
Article
ISSN
0090-6980

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The synthetic prostaglandin analogue cloprostenol has been prepared radiolabelled with 14C. The isotopic abundance of 14C at position C-15 was greater than 90% of the theoretical maximum. We have utilizted the high abundance of the 14C isotope for metabolism studies by preparing mixtures of [12C]:[1