The use of tissue plasminogen activator in postvitrectomy cases
β Scribed by Chryssanthi Koutsandrea; Michalis Apostolopoulos; Panagiotis Theodossiadis
- Publisher
- Springer Netherlands
- Year
- 1993
- Tongue
- English
- Weight
- 874 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0165-5701
No coin nor oath required. For personal study only.
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## Abstract Although originally known as a plasma serine protease involved in clot dissolution, tPA and its primary inhibitor, PAIβ1, play crucial roles in synaptic reorganization and plasticity in the central nervous system. In contrast to the wide array of work conducted in neural cells, relative
Tissue plasminogen activator (tPA), a widely used thrombolytic agent, has an application limit due to short half-life. To prolong the half-life of tPA, liposomes composed of egg phosphatidylcholine (EPC), cholesterol (CHOL) and sodium cholesterol-3-sulfate (CS) were prepared by lipid film method. In