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Disturbances in the tissue plasminogen activator/plasminogen activator inhibitor (TPA/PAI) system in systemic lupus erythematosus

✍ Scribed by Dr. Guillermo J. Ruiz-Argüelles; Alejandro Ruiz-Argüelles; Eduardo Lobato-Mendizábal; Felipe Díaz-Gomez; Elda Pacheco-Pantoja; Cristina Drenkard; Donato Alarcón-Segovia


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
497 KB
Volume
37
Category
Article
ISSN
0361-8609

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The urokinase-type plasminogen activator
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The urokinase-type plasminogen activator (u-PA) system consists of the serine proteinases plasmin and u-PA; the serpin inhibitors a 2 -anti-plasmin, PAI-1 and PAI-2; and the u-PA receptor (u-PAR). Two lines of evidence have strongly suggested an important and apparently causal role for the u-PA syst