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The use of reverse immunology to identify HLA-A2 binding epitopes in Tie-2

✍ Scribed by Judith M. Ramage; Ian Spendlove; Robert Rees; Robert S. Moss; Lindy G. Durrant

Book ID
105966998
Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
249 KB
Volume
55
Category
Article
ISSN
0340-7004

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Identification of an HLA-A*0201 cytotoxi
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✍ Judith M. Ramage; Rachael Metheringham; Andrew Conn; Ian Spendlove; Robert S. Mo πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 160 KB

## Abstract Tie‐2 stabilises pericyte–endothelial interactions during angiogenesis and is highly expressed on endothelium during several diseases, including arthritis, age‐related macular degeneration and cancer. A vaccine that targets endothelium overexpressing Tie‐2 may result in vessel damage an