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The use of chimeric A2Kb tetramers to monitor HLA A2 immune responses in HLA A2 transgenic mice

✍ Scribed by E.M Choi; M Palmowski; J Chen; V Cerundolo


Book ID
114051095
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
399 KB
Volume
268
Category
Article
ISSN
0022-1759

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## Abstract We identified the strategies to induce a CTL response to human papillomavirus (HPV) 16 E2 in HLA‐A2 transgenic mice (AAD). A chimeric HPV16 virus‐like particle (VLP) that includes full length HPV16 E7 and E2 (VLP‐E7E2) was generated. The combination of E2 and E7 has the advantage that E