✦ LIBER ✦

The use of reactive collisions in tandem mass spectrometry for the differentiation of isomeric structures

✍ Scribed by Dean D. Fetterolf; Richard A. Yost; John R. Eyler

Publisher: John Wiley and Sons
Year: 1984
Tongue: English
Weight: 226 KB
Volume: 19
Category: Article
ISSN: 1076-5174
DOI: 10.1002/oms.1210190212

No coin nor oath required. For personal study only.

✦ Synopsis

LE,TERS TO THE EDITOR standard automatic subtraction programmes. The spectra obtained showed more clearly ions indicative of molecular weight ([M -H]-) and sugar sequence than those recorded using a glycerol matrix. Figures 2, 3 and 4 illustrate, respectively, typical low resolution spectra of di-, tri-and tetrasaccharides that are composed entirely of hexose units. Peaks marked with an asterisk define sugar sequence, corresponding to consecutive losses of hexcse residues (162 u) from [M-HI-ions, which are highly abundant in all cases. 'Doping' of the PEG200 matrix with salts is not necessary to obtain good spectra of such carbohydrates. For high resolution studies, the solvent would not be PEG200 but the poly(ethy1eneglycol) mixture used for calibration (see caption to Fig. 1). Interpolation from the reference peaks supplied (Table 1) leads to accurate mass assignment.

📜 SIMILAR VOLUMES

Differentiation Between the Isomeric Ami

Differentiation Between the Isomeric Amino Acids Leucine and Isoleucine Using Low-Energy Collision-Induced Dissociation Tandem Mass Spectrometry

✍ Hulst, A. G.; Kientz, C. E. 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 206 KB 👁 1 views

The Coordinated Use of Tandem Mass Spect

The Coordinated Use of Tandem Mass Spectrometry and High Resolution Mass Spectrometry for the Structure Identification of the Kedarcidin Chromophore

✍ Lee, Mike S.; Klohr, Steven E.; Kerns, Edward H.; Volk, Kevin J.; Leet, John E.; 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 724 KB

Structure identification strategies for kedarcidin chromophore are described using tandem mass spectrometry (MS/MS) and high-resolution MS techniques. The strategy involves dividing a large, complex natural product molecule into several smaller molecules (substructures) to simplify identification. S

The analysis and characterization of iso

The analysis and characterization of isomeric metabolites of temelastine by the combined use of thermospray liquid chromatography/mass spectrometry and liquid chromatography/tandem mass spectrometry

✍ Timothy J. A. Blake; Iain G. Beattie 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 534 KB

Study of the collision-induced radical c

Study of the collision-induced radical cleavage of flavonoid glycosides using negative electrospray ionization tandem quadrupole mass spectrometry

✍ Erlend Hvattum; Dag Ekeberg 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 215 KB

## Abstract Negative electrospray ionization tandem quadrupole mass spectrometry was used to study the collision‐induced dissociation (CID) of the __O__‐glycosidic bond from different commercially available flavonoid glycosides. Depending on the structure, flavonoid glycosides can undergo both a co

The Role of Isotope Dilution Mass Spectr

The Role of Isotope Dilution Mass Spectrometry in the Development of Tandem Mass Spectrometry for Quantitative Organic Analysis

✍ Kenneth S. Webb; David Carter 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 86 KB 👁 2 views

Tandem mass spectrometry (MS/MS) has the significant advantage of improving selectivity and overcoming interferences present in conventional mass spectrometry. The quantitative use of MS/MS is discussed with reference to sources of instrumental error and ways to minimize such errors. Key parameters

Use of liquid chromatography–tandem mass

Use of liquid chromatography–tandem mass spectrometry for the analysis of pentoxifylline and lisofylline in plasma

✍ Patrick B. Kyle; Kim G. Adcock; Robert E. Kramer; Rodney C. Baker 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 130 KB 👁 3 views