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The use of PIG-A as a sentinel gene for the study of the somatic mutation rate and of mutagenic agents in vivo

✍ Scribed by Benedetta Peruzzi; David J. Araten; Rosario Notaro; Lucio Luzzatto

Book ID
113809754
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
928 KB
Volume
705
Category
Article
ISSN
1383-5742

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## Abstract We previously reported that rat spleen T‐cells and peripheral red blood cells that are deficient in glycosylphosphatidylinositol (GPI) synthesis [presumed mutants for the phosphatidylinositol glycan complementation group A gene (__Pig‐A__)] could be detected by flow cytometry (FCM) as c