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The use of peptones as medium additives for the production of a recombinant therapeutic protein in high density perfusion cultures of mammalian cells

✍ Scribed by Rüdiger Heidemann; Chun Zhang; Hanshi Qi; James Larrick Rule; Carl Rozales; Sinyoung Park; Sandra Chuppa; Manas Ray; James Michaels; Konstantin Konstantinov; David Naveh

Book ID
110259980
Publisher
Springer
Year
2000
Tongue
English
Weight
328 KB
Volume
32
Category
Article
ISSN
0920-9069

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Combined approach of NMR and chemometrics for screening peptones used in the cell culture medium for the production of a recombinant therapeutic protein
✍ Ying Luo; Guoxiang Chen 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 197 KB 👁 2 views

## Abstract Soy peptones or soy hydrolysates are widely used as key medium additives in serum‐free cell culture processes for industrial production of therapeutic recombinant proteins. The heterogeneous nature of these vegetable‐derived materials can lead to substantial lot‐ to‐lot variability in c