Application of near-infrared (NIR) spectroscopy for screening of raw materials used in the cell culture medium for the production of a recombinant therapeutic protein

Combined approach of NMR and chemometric

Combined approach of NMR and chemometrics for screening peptones used in the cell culture medium for the production of a recombinant therapeutic protein

✍ Ying Luo; Guoxiang Chen 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 197 KB 👁 1 views

## Abstract Soy peptones or soy hydrolysates are widely used as key medium additives in serum‐free cell culture processes for industrial production of therapeutic recombinant proteins. The heterogeneous nature of these vegetable‐derived materials can lead to substantial lot‐ to‐lot variability in c