The use of new chiral phosphite and amidophosphite ligands in the Rh-catalyzed hydrogenation of dehydro-β-amino acid derivatives
✍ Scribed by Lyubimov, S. E.; Rastorguev, E. A.; Petrovskii, P. V.; Davankov, V. A.
- Book ID
- 111902218
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 271 KB
- Volume
- 60
- Category
- Article
- ISSN
- 1573-9171
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## Abstract New chiral amidophosphite ligand was synthesized and tested in the Rh‐catalyzed asymmetric hydrogenation of (__Z__)‐β‐(acylamino)acrylates in protic solvents and supercritical carbon dioxide (scCO~2~) The catalytic performance is affected greatly by the acidity of the solvents. Better e
We developed an efficient, easily available, and easy to use proline amide-based ruthenium(II) catalysts for the asymmetric hydride transfer reduction of prochiral ketones and e.e.s up to 98.8% have been measured.