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The Use of Mitochondrial DNA Single Nucleotide Polymorphisms to Assist in the Resolution of Three Challenging Forensic Cases

✍ Scribed by Rebecca S. Just; Mark D. Leney; Suzanne M. Barritt; Christopher W. Los; Brion C. Smith; Thomas D. Holland; Thomas J. Parsons


Book ID
109280485
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
77 KB
Volume
54
Category
Article
ISSN
0022-1198

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We report the outcome of two prenatal analyses for the T to G mutation at nucleotide 8993 in the mitochondrial DNA. This mutation is associated with neurogenic muscle weakness, ataxia and retinitis pigmentosa (NARP) and the neurodegenerative condition, Leigh syndrome. One prospective mother was the