A clinical pharmacogenetic model to pred
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Judith A. M. Wessels; Sjoerd M. van der Kooij; Saskia le Cessie; Wietske Kievit;
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Article
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2007
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John Wiley and Sons
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English
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## Abstract ## Objective To develop a clinical pharmacogenetic model to predict the efficacy of methotrexate (MTX) in rheumatoid arthritis (RA). ## Methods Two hundred five patients with newly diagnosed RA and active disease were treated with MTX (initiated at a dosage of 7.5 mg/week and increas