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The use of mini-dose suxamethonium to facilitate the insertion of a laryngeal mask airway

โœ Scribed by K. M. Ho; P. T. Chui


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
71 KB
Volume
54
Category
Article
ISSN
0003-2409

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โœฆ Synopsis


The use of miniโ€dose suxamethonium to facilitate the insertion of a laryngeal mask airway was investigated. Sixty patients were assigned randomly in a doubleโ€blind manner to receive 0.9% sodium chloride or suxamethonium 0.1โ€ƒmg.kg^โˆ’1^ intravenously, following intravenous induction with propofol 2.5โ€ƒmg.kg^โˆ’1^. The laryngeal mask was inserted after the first attempt in 87% of patients. Miniโ€dose suxamethonium improved the correct positioning of the laryngeal mask during the first attempt (93 vs. 67%, pโ€ƒ<โ€ƒ0.02), decreased the incidence of swallowing (pโ€ƒ<โ€ƒ0.001), gagging (pโ€ƒ<โ€ƒ0.001) and head or limb movement (pโ€ƒ<โ€ƒ0.05). Laryngeal mask insertion was graded as easy in 93% of patients who had miniโ€dose suxamethonium, compared with 60% in the placebo group (pโ€ƒ<โ€ƒ0.01). The duration of apnoea between the two groups was not significantly different (0.54 vs. 0.61โ€ƒmin, pโ€ƒ=โ€ƒ0.46). The total dose of propofol needed to insert the laryngeal mask was lower in the suxamethonium group (2.57 vs. 3.25โ€ƒmg.kg^โˆ’1^, pโ€ƒ<โ€ƒ0.01) and was associated with less hypotension (pโ€ƒ<โ€ƒ0.05). Fasciculation (17%) and mild myalgia (23%) were common despite the small dose of suxamethonium used. In conclusion, miniโ€dose suxamethonium facilitates laryngeal mask insertion. Myalgia is common and the technique is not recommended for patients who are prone to suxamethonium myalgia.


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