The use of intermediate dose cytosine arabinoside (ID Ara-C) in the treatment of acute non-lymphocytic leukaemia in relapse
β Scribed by H. C. van Prooijen; A. W. Dekker; K. Punt
- Book ID
- 114710195
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 509 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0007-1048
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Clofarabine (40Β mg/m^2^/dayβΓβ5) and high-dose cytosine arabinoside (Ara-C, 1β2Β g/m^2^/dayβΓβ5) were used in 10 men and 11 women, at a median age of 45 (22β62)βyears, with refractory (__N__β=β4) and relapsed (__N__β=β17) acute myeloid leukaemia, after a median of 3 (2β5) prior regimens. Grade 4 myel
## Background: The objectives of the study were to evaluate the antileukemic efficacy and toxicity profiles of the combination of fludarabine and intermediate-dose cytosine arabinoside (ara-c) in refractory or relapsed adult acute lymphocytic leukemia (all). patients and methods. thirty adults with
Effective treatment of the elderly patients (265 years) with acute nonlymphocytic leukemia (ANLL) remains elusive and controversial. In the present study, single-agent Cytosine Arabinoside (AM-C) was administered at an intermediate dose level (500 mg/m2 intravenously [I.V.] I-hour infusion q12 hours