Background and Objective: Photodynamic therapy (PDT) has been established as an alternative therapy for the treatment of various types of malignant disorders, including oesophageal, lung, and bladder cancer. However, one of the limitations of PDT is treatment-induced hypoxia that triggers angiogenes
THE USE OF HYDROGEN PEROXIDE TO ENHANCE THE EFFICACY OF DOXORUBICIN HYDROCHLORIDE IN A MURINE BLADDER TUMOR CELL LINE
β Scribed by LOUGHLIN, KEVIN R.; MANSON, KELLEDY; CRAGNALE, DINO; WILSON, LISE; BALL, ROBERT A.; BRIDGES, KENNETH R.
- Book ID
- 122975807
- Publisher
- Lippincott Williams and Wilkins
- Year
- 2001
- Tongue
- English
- Weight
- 831 KB
- Volume
- 165
- Category
- Article
- ISSN
- 0022-5347
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## Methods Mitoxantrone was purchased from Lederle (France) and doxorubicin from Dakota (France). Stock solutions stored at Οͺ20Β°C (9 Ο« 10 Οͺ4 M for doxorubicin and 4 Ο« 10 Οͺ3 M for mitoxantrone) and dilutions of doxorubicin and mitoxantrone were freshly prepared in physiological saline solution, NaC
## Abstract The aim of this work was to investigate the response of the antioxidant defense system to two oxidative stressors, hydrogen peroxide and __tert__βbutyl hydroperoxide, in HepG2 cells in culture. The parameters evaluated included enzyme activity and gene expression of superoxide dismutase