𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The use of high-pressure liquid chromatography in the preparation of tritium-labeled chloramphenicol and its analogs

✍ Scribed by Jackie L. Martin; Anne M. Taburet; Lance R. Pohl

Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
339 KB
Volume
96
Category
Article
ISSN
0003-2697

No coin nor oath required. For personal study only.

✦ Synopsis

The I-hydroxy epimers of chloramphenicol and thiamphenicol formed from the reduction of the respective 1-0x0 derivatives with [3H]NaBH, have been separated preparatively by high-pressure liquid chromatography on a PBondapak C,, column. This separation procedure permits the facile and rapid preparation of the l-3H-labeled derivatives of chloramphenicol and its analogs.

πŸ“œ SIMILAR VOLUMES

1-dehydrohexestrol. Synthesis of a precu
1-dehydrohexestrol. Synthesis of a precursor for the preparation of tritium-labeled hexestrol derivatives and its use in a new, convenient synthesis of tritium-labeled o-azido-hexestrol
✍ Ramanuj Goswami; Michael R. Kilbourn; John A. Katzenellenbogen πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 French βš– 482 KB πŸ‘ 1 views

## Abstract __Erthro__‐1‐dehydrohexestrol (**4a**), an analog of the nonsteroidal estrogen __meso__‐hexestrol containing a double bond in the side chain, has been synthesized as a general precursor for the preparation of tritium‐labeled hexestrol derivatives. It can be functionalized further as nee

The use of the acetonide derivative in t
The use of the acetonide derivative in the preparation of D-threo-chloramphenicol-1-3H and its nitroso derivative
✍ J. Richard Heys πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 French βš– 432 KB

## Abstract An efficient synthesis of millimolar quantities of high specific activity D‐__threo__‐chloramphenicol‐1‐^3^H is described. The key step is the chromatographic separation of the compound from its 1‐epimer, produced in the Ca(B^3^H~4~)~2~ reduction of chloramphenicol ketone (D‐α‐dichloroa

A novel method for the separation and qu
A novel method for the separation and quantitation of benzene metabolites using high-pressure liquid chromatography
✍ William F. Greenlee; John P. Chism; Douglas E. Rickert πŸ“‚ Article πŸ“… 1981 πŸ› Elsevier Science 🌐 English βš– 312 KB

A method for the separation of benzene metabolites using reverse-phase high-pressure liquid chromatography is described. The antoxidant, ascorbic acid is added to an aqueous mixture of 1,2&benzenetriol, hydroquinone, catechol, and phenol, to prevent autooxidation. The eluting solvents are equilibrat