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The Use of Genetically Modified Embryonic Stem Cells to Generate Transgenic Mice

✍ Scribed by M. V. Pryzhkova; I. R. Zakeeva; A. V. Kibardin; G. P. Georgiev; S. L. Kiselev

Book ID
111608770
Publisher
SP MAIK Nauka/Interperiodica
Year
2004
Tongue
English
Weight
77 KB
Volume
40
Category
Article
ISSN
1022-7954

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## Abstract Transgenic and gene‐targeted mutant mice provide powerful tools for analysis of the cellular processes involved in early development and in the pathogenesis of many diseases. Here we describe a transgene integration strategy mediated by site‐specific recombination that allows establishm