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Rapid Generation of Stable Transgenic Embryonic Stem Cell Lines Using Modular Lentivectors

โœ Scribed by David M. Suter; Laetitia Cartier; Esther Bettiol; Diderik Tirefort; Marisa E. Jaconi; Michel Dubois-Dauphin; Karl-Heinz Krause


Book ID
111843608
Publisher
AlphaMed Press
Year
2006
Tongue
English
Weight
660 KB
Volume
24
Category
Article
ISSN
1066-5099

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Other transgenic mutation assays: Develo
โœ Vasily N. Dobrovolsky; Daniel A. Casciano; Robert H. Heflich ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 663 KB

A tk+/mouse embryonic stem (ES) cell line, designated 1G2, has been created in which one allele of the thymidine kinase (tk) gene was inactivated by targeted homologous recombination. This line is an analog of the mouse lymphoma tk+/-L5 178Y cell line, which is used widely to assess the mutagenicity