A five-.step synthesis of the above substances from ethy2 phenylthioacetate and I-bromotetradecane is described.
The use of d-ribonolactone in organic synthesis. I. total synthesis of (−)-litsenolides C1 and C2.
✍ Scribed by Shin-Yih Chen; Madeleine M. Joullie
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 225 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
D-Ribonolactone, an inexpensive, commercially available sugar, has been transformed stereoselectively into naturally occurring lactones, the litsenolides Cl and C2.
During the course of chemical studies on Litsea Japonica (Thunb) Juss., a plant
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Luminacins C 1 and C 2 (1 and 2), novel angiogenesis inhibitors, have been synthesized from a carbohydrate. The correlation of 1 and 2 confirms their structures to be different only at C1%% and establishes the relative and absolute configurations.