The first total synthesis and establishment of absolute structure of luminacins C1 and C2

✍ Scribed by Kuniaki Tatsuta; Satoshi Nakano; Fumie Narazaki; Yusuke Nakamura

• Publisher: Elsevier Science
• Year: 2001
• Tongue: French
• Weight: 147 KB
• Volume: 42
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)01657-4

✦ Synopsis

Luminacins C 1 and C 2 (1 and 2), novel angiogenesis inhibitors, have been synthesized from a carbohydrate. The correlation of 1 and 2 confirms their structures to be different only at C1%% and establishes the relative and absolute configurations.