The use of concomitant serum pyruvate-kinase (PK) and creatine-phosphokinase (CPK) for carrier detection in Duchenne's muscular dystrophy through discriminant analysis
โ Scribed by Mayana Zatz; Paulo A. Otto
- Book ID
- 118929222
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 339 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0022-510X
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๐ SIMILAR VOLUMES
## Abstract In the absence of an unambiguous test for identifying Duchenne muscular dystrophy (DMD) heterozygotes, methods are needed for combination of the results of individually equivocal tests as effectively and rationally as possible. We used logistic discrimination to assess the effectiveness
The serum activity of creatine kinase (CK) and pyruvate kinase (PK) was measured in 98 pairs of same-sex Brazilian twins. The purpose of this study was to estimate the genetic and environmental components of serum activity levels for both enzymes. Heritabilities were estimated separately by path ana