The use of carbon-14 as a secondary counting standard for sulphur-35
β Scribed by J.P. Buckley
- Publisher
- Elsevier Science
- Year
- 1971
- Weight
- 187 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0020-708X
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## Abstract Irbesartan (Avapro^β’^) is in clinical use as an antihypertensive drug. It is a nonpeptide angiotensin II receptor antagonist. A radiolabeled version of this drug, intended for use in environmental fate studies, was prepared from __N,N__βdimethyl[^14^C]formamide. Our method of synthesis
The organic samples triply labeled with 3H, 14C, and 35S were combusted in a flow-type combustion flask under a continuous oxygen flow. The oxygen gas containing the combustion products, which were mainly 3H2O, 14CO2, and 35SO2, was introduced into successive 0.5 M H2O2 and Oxisorb (2-methoxyethylam