✦ LIBER ✦

The use of capillary gas chromatography/mass spectrometry for the determination of acidic dopamine metabolites in human brain

✍ Scribed by Yvette Michotte; Dirk Deleu; Guy Ebinger

Publisher: John Wiley and Sons
Year: 1985
Tongue: English
Weight: 322 KB
Volume: 12
Category: Article
ISSN: 1076-5174
DOI: 10.1002/bms.1200121206

No coin nor oath required. For personal study only.

✦ Synopsis

A capillary gas chromatographichnass spectrometric method was developed for the determination of homovanillic acid and 3,4-dihydroxyphenylacetic acid in discrete areas of human brain known to contain only small amounts of dopamine metabolites. The electron impact mass spectra of the trimethylsilyl derivatives of homovanillic acid and 3,4-dihydroxyphenylacetic acid and their deuterated isotopic variants were used for their identification and quantification.

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