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The use of a light-sensitive phosphate protecting group for some mononucleotide syntheses

✍ Scribed by M. Rubinstein; B. Amit; A. Patchornik


Publisher
Elsevier Science
Year
1975
Tongue
French
Weight
179 KB
Volume
16
Category
Article
ISSN
0040-4039

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The first synthesis of N-Boc-protected tropanes by a [4+3] cycloaddition reaction is described. The Boc group has been cleanly removed demonstrating that this group would be very useful for the synthesis of 'tropane-like' scaffolds for combinatorial chemistry.